Biosensing

In today’s world, rapid diagnostic testing is widely recognized for its convenience and speed. Typically, these tests provide a single result for one disease or condition, with occasional exceptions like combined Flu and Covid tests. However, expanding the number of test points within a single kit presents significant challenges, particularly due to cross-reactions between antigens and antibodies.

This is where label-free diagnostics step in, offering a promising alternative. Label-free sensing technologies, such as Surface Plasmon Resonance (SPR), Localized Surface Plasmon Resonance (LSPR), and Extraordinary Optical Transmission (EOT), provide solutions to these challenges.

The image on the right showcases a serial dilution of glycerol detected using a nanopattern-based EOT sensor, illustrating the potential of label-free diagnostics in advancing biosensing technologies.

EOT sensors manufactured using NanoTerrane technology enable advanced multiplex label-free biosensing. The image on the left illustrates a reader device that monitors light propagation through the sensor. This device is equipped with a single-use cartridge containing the sensor, an on-chip pump, and a microfluidic system to deliver the sample. The integrated software simplifies the analysis of binding kinetics, facilitating detailed and efficient biosensing.