Nanotopography has a profound impact on cell behavior, offering a new frontier in cellular research. Over the past decade, numerous studies have demonstrated that nanoscale cues can significantly influence stem cell proliferation and differentiation. Cells grown on nanopatterned surfaces have shown remarkable potential, particularly in the field of biologics.

The image on the right illustrates this effect. These adipose-derived mesenchymal stem cells were cultured in a single dish, with images captured from various regions, each featuring distinct nanopatterns. Notably, the cells were grown without any additional supplements—only DMEM, FBS, and antibiotics were used—highlighting the intrinsic power of the nanoscale environment.